After taking a first-pitch strike from fireball White Sox closer Bobby Jenks, the Red Sox shortstop chopped a grounder to the left of the pitcher's mound.
Tadahito Iguchi moved ever so slightly to his right, fielded the ball between his legs and threw onto Paul Konerko, beating Renteria, who was brought to Boston to help the Red Sox repeat their historic title of 2004, by two steps, beginning yet another celebration. This year though, it was the White Sox who were jubilant.
Ending a postseason series is nothing new for Renteria. In 1997, it was his line drive past the glove of Charles Nagy in Game 7 that delivered the first of two World Series titles to the Florida Marlins.
Last season is still fresh in the minds of fans everywhere, especially in St. Louis and Boston. Keith Foulke jumped in the air to grab a Renteria bouncer before flipping an underhand toss to Doug Mientkiewicz for the first Red Sox's title since 1918.
So there was sad irony among those same Boston fans in attendance at Fenway on Friday, watching White Sox fans celebrate on their turf much the same way Red Sox fans did in New York and St. Louis last year.
Renteria wasn't that interested as he turned away, dipped his head in disappointment and made his way to the Red Sox clubhouse, beginning an offseason likely spent hoping for a happier ending.
Mike Petraglia is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.