Pena and Mohr both went deep in Wednesday's loss.
"That was nice to see," said Red Sox manager Terry Francona. "We are going to face left-handers coming up. If [Mohr] and Wily Mo can give us a little bit of a lift, that would be big for us.
The Red Sox could also use a surge of offense from star slugger Manny Ramirez, who is hitting .214 and is still looking for his first home run.
BOS: RHP Matt Clement (1-0, 5.14 ERA)
The right-hander came out strong in his first start, firing six shutout innings before giving up four runs in his last inning of work. He recorded the victory over the Orioles. This is Clement's first start of the season at Fenway Park, where he went 8-4 with a 4.90 ERA last year. Clement pitched four times against the Blue Jays in 2005, going 0-2 with an 8.34 ERA.
TOR: LHP Ted Lilly (1-0, 4.05 ERA)
Lilly will be making his second start of the year, this time against the Red Sox, who the left-hander victimized last season. In 2005, Lilly was 3-0 with a 2.40 ERA in five starts with 19 strikeouts across 30 innings vs. Boston. He hasn't fared as well at Fenway Park, though, going 2-1 with a 5.08 ERA in seven starts in Beantown.
Player to watch
David Ortiz has gone deep the last two games. He has belted 21 homers in his career against the Blue Jays, his highest total against any opponent
On the Internet
Official game notes
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Friday: Red Sox (Curt Schilling, 2-0, 1.93 ERA) vs. Mariners (Jamie Moyer, 0-1, 4.38 ERA), 7:05 p.m. ET
Saturday: Red Sox (Tim Wakefield, 1-1, 6.52 ERA) vs. Mariners (Joel Pineiro, 1-1, 5.40 ERA), 1:20 p.m. ET
Sunday: Red Sox (Josh Beckett, 2-0, 1.29 ERA) vs. Mariners (Jarrod Washburn, 1-1, 6.00 ERA), 7:05 p.m. ET