Manager Terry Francona said both players would work out with the Red Sox on Tuesday before the opener of a three-game series at Camden Yards against the Orioles and then be activated Wednesday.
Patterson, who played center field and was 0-for-4 with the PawSox on Monday night, was placed on the 15-day disabled list Aug. 17, retroactive to Aug. 16, with a neck strain. Saltalamacchia, who caught and went 1-for-3 on Monday night, was disabled on Aug. 19, retroactive to Aug. 16, with an infection in his right lower leg.
Francona is particularly interested in seeing how Saltalamacchia, acquired July 31 from Texas in exchange for three Minor Leaguers and cash considerations, works behind the plate. Saltalamacchia could also get a look at first base, the manager said.
"[Saltalamacchia] hasn't played very much [first base]," Francona said. "We're obviously interested to watch him catch. He's gone out to first base, but it hasn't been very much."
General manager Theo Epstein said that the Red Sox could summon one more player from Pawtucket once rosters expand, but not before the PawSox's season ends on Labor Day.
Epstein cautioned against reading too much into players' performances over the season's final weeks as a gauge of future production.
"September can be a misleading time to evaluate players based on performance. But it's not a bad time if you're getting to know a player," Epstein said. "Find out what makes him tick, get a first-hand read on his skills, his tools, the way they apply to the game, and someone's instincts, too. I think September can be valuable [in that way]."
Pete Kerzel is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.