But the Red Sox were gratified to know that Youkilis had merely suffered a minor injury that could have happened in any kind of weather. The first baseman rolled his left ankle on the grass while making his turn out of the box.
Eric Hinske replaced Youkilis in the bottom of the inning.
Though the ankle remained swollen after the game, Youkilis was confident he'll be in the lineup Sunday night when the Sox try to avoid getting swept out of Texas.
"Tito [Francona] just said to come in and ice it so I can be ready for tomorrow," said Youkilis. "It's nothing like a sprain or anything. I just rolled it. It's a little sore right now, but I'll tape it up and go tomorrow."
Hinske showed no rust in his first action of the season, belting a single.
Timlin's tuneup: Mike Timlin made what was expected to be his final Minor League tuneup on Saturday, pitching one inning for Triple-A Pawtucket. In a game played at Charlotte, Timlin gave up a hit and a run. He had no walks and no strikeouts. Seven of Timlin's 10 pitches were for strikes.
The veteran is going to spend Easter at home with his family in Florida and then is likely to be activated for the home opener on Tuesday.
Reserves to shake off rust: Over the first five games of the season, backup catcher Doug Mirabelli was the only reserve to get a start. That will change Sunday, when Francona is expected to insert Alex Cora into the lineup at second base.
With the Mariners perhaps throwing multiple lefties during the three-game series in Boston next week, Wily Mo Pena will probably make a start in one of those games. Hinske will also get in there at some point during the seven-game homestand.
"When we get home, we have some crazy starting times," Francona said. "We have a 2 o'clock, a 7 o'clock, a 3:55, we'll make sure everybody plays a game. We'll get everybody in and take the edge off and kind of get in a routine."
Have a question about the Red Sox?
E-mail your query to MLB.com Red Sox beat reporter Ian Browne for possible inclusion in a future Inbox column. Letters may be edited for brevity, length and/or content.
Cold in the heart of Texas: How cold was it by Texas standards on Saturday night? The 38-degree temperature at game-time was the coldest since the inception of Rangers Ballpark in Arlington in 1994.
"You know what, it's cold," Francona said. "What are you going to do? I hope we hit the ball hard enough where we have to run the bases. Yesterday, we prevented it."
In the first inning alone, the Sox topped their production of Friday by scoring a run and getting three hits. In Friday's game, the Sox were shut out and only had three hits in the entire game.
On deck: Ace Curt Schilling looks to rebound from his shaky performance on Opening Day when he takes the mound in Sunday night's ESPN telecast against the Rangers, who counter with right-hander Vicente Padilla. First pitch is scheduled for 8:05 p.m. ET.
Ian Browne is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.