BOS: LHP Jon Lester (1-0, 4.26 ERA)
Lester has been everything Boston management wanted since he returned from anaplastic large cell lymphoma treatment and Triple-A rehab on July 23. He won his first game, against the powerful Cleveland Indians, and pitched well enough for Boston to win a July 28 game against Tampa Bay.
SEA: LHP Horacio Ramirez (6-3, 6.52 ERA)
Ramirez, acquired from the Atlanta Braves in a trade that lost the Mariners Rafael Soriano, has struggled mightily in Seattle. He has allowed 80 hits in just 58 innings, walking as many batters (24) as he has struck out.
Red Sox left fielder Manny Ramirez, who hit the team's only homer on May 3 against Horacio Ramirez at Fenway, isn't the only Boston player to touch up the Seattle starter. Lowell hammered Ramirez as a member of the National League East's Florida Marlins. He owns nine hits in 18 at-bats against him, with a home run. Tickets
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Saturday: Red Sox (Daisuke Matsuzaka, 12-8, 3.75) at Mariners (Jarrod Washburn, 8-7, 4.11), 10:05 p.m. ET
Sunday: Red Sox (Josh Beckett, 13-5, 3.41)at Mariners (Miguel Batista, 11-7, 4.23), 4:05 p.m. ET
Monday: Red Sox (Curt Schilling, 6-4, 4.20) at Angels (Jered Weaver, 7-5, 4.00), 10:05 p.m. ET
Alex McPhillips is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.