The Red Sox play the Mariners in a 4:05 p.m. ET contest that day. The ceremony is expected to start at 3:30.
This will mark the third time Wakefield will take part in Fenway festivities this season.
He was honored along with former team captain Jason Varitek in a first-pitch ceremony at the team's home opener on April 13.
And one week later, Wakefield participated in the 100th anniversary celebration of Fenway Park, poignantly pushing Bobby Doerr in a wheelchair to his position at second base while Varitek did the same for retired shortstop Johnny Pesky.