After popping out to shortstop in the first inning, Ortiz jumped on a 1-2 fastball by Virgil Vasquez and lined a shot that kissed off the top of the right-field fence and into the visitors' bullpen for a home run.
Ortiz's blast ignited a seven-run inning, which ended when Ortiz lined out to first baseman Fernando Seguiginol.
Big Papi completed his night's work by walking on a 3-2 pitch in the sixth.
Given the nature of Ortiz's hacks, it was obvious even to the most casual fan that he wasn't holding anything back, that he wasn't subconsciously thinking that he might re-injure his wrist.
"I've been swinging like I normally do," he said. "If anything happens, I can feel it and would stay away from playing until I get to be fine. Even in batting practice, I was trying to swing as hard as I can.
"Everything came out pretty good tonight."
In retrospect, Ortiz gave an indication of things to come in BP when he hit 11 home runs, including one that bounced halfway up the roof of a concession stand behind the center-field fence, which is 400 feet from home plate.
And when he came to bat in the sixth, he might very well have imagined he was at Fenway Park because the SRO crowd of 11,460 -- many of whom were wearing Ortiz jerseys -- at McCoy Stadium were shouting "Papi, Papi."
"That's exactly what it's like at Fenway," said Ortiz, who even received an ovation when he stepped on the field for pre-game stretching and sprinting. "When they start calling your name, it kind of pumps you up."
But more important than Ortiz's feeling like he was at home was the fact that his timing and pitch recognition were better than might have been expected since he's been idle for 38 days.
"I was fine tonight," he said. "I saw pitches. I chased a few high fastballs, but other than that I was taking bad pitches. That's how you work on your timing.
"I put a good swing [on the home run]. That's my game. To be able to swing like that when I had an injury that prevented me from holding onto my bat is a good feeling."
Understandably, expectations are high for Ortiz, given his past performance.
"I really don't feel any pressure because I'm used to playing at Fenway," Ortiz said. "You can't get any more pressure than playing there. This is fun and relaxing. But if I strike out, it would be like 'He hasn't played in a while.'"
But Ortiz didn't strike out.
Initially, Ortiz was supposed to play in only three games with Pawtucket, take off Sunday and then play three at Portland. But Ortiz asked Red Sox head trainer Paul Lessard about the possibility of playing four games with the PawSox.
Lessard obtained approval from manager Terry Francona, but Ortiz still reserved the option to bypass Sunday's game if his wrist is hampering him.
Moreover, regardless of how well he hits with Pawtucket, he's not about to pressure the Red Sox to rejoin the team on the West Coast and skip Portland.
"I want to play all seven games," Ortiz said, emphatically.