The Sox replaced Crisp with Jacoby Ellsbury in center. Ellsbury then took right fielder Mark Kotsay's spot as leadoff man on the night, with Kotsay moving to sixth in the lineup and third baseman Jed Lowrie taking Crisp's spot batting seventh.
"He was sitting in the dugout, right before they were going out to run," manager Terry Francona said after the Red Sox's 8-0 victory. "He was sitting there talking to Kotsay. He went out and ran and came back in -- it was literally 10 minutes before the game. He said, 'I'm not feeling well.' So we ran in and grabbed Ellsbury and made the switch."
Crisp last played Wednesday against New York at Yankee Stadium, going 1-for-4 in the contest with an RBI. He's batting .263 with seven homers and 33 RBIs this season for the Red Sox.
Ellsbury went 0-for-4 in the contest with a run scored and a walk and made a sparkling defensive play to rob White Sox leadoff hitter Orlando Cabrera in the first inning.
Mark Remme is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.