Daisuke Matsuzaka had four and relievers Manny Delcarmen and Justin Masterson each had one. Backup catcher George Kottaras was catching Matsuzaka for the first time in a regular-season game.
"I think that puts him in a difficult position," manager Terry Francona said of Kottaras. "This guy's not caught a lot to begin with. And when there's runners on base, your first thought is to get down and keep it in front of you. There were a couple that were way out there. I can see where that doesn't lend itself to being real comfortable back there."
Matsuzaka's four wild pitches tied a club record set on Sept. 14, 1929, by Milt Gaston.
"I think sometimes you need a lot of experience to see how you are going to pitch in certain situations to certain hitters, and there were cases out there today that our signs didn't match up all the time or our timing didn't match up," Matsuzaka said through a translator. "All that comes from experience. I think I needed to take more of a leadership role out there with respect to working with Kottaras today."
"I was trying to do my best just to help Daisuke through it, and even our team," Kottaras said. "I just wanted to keep us in the ballgame and he did. We just didn't put things together."
"George's Canadian background came into play there," manager Terry Francona said. "He looked like a goalie at times. There were a lot of balls bouncing, guys moving up or potentially moving up."
Justin Masterson was asked after the game if he knew that the six wild pitches had tied a modern record.
"No, but I'm glad I could be in the books for one," Masterson joked.
It was only the fifth time since 1900 that a team has thrown six wild pitches in a game. The California Angels were the last team to do so, throwing six against the Twins on April 13, 1991.
The wild pitches, ironically, didn't have a huge impact on the game. None led directly to runs and only one even led indirectly to a run. Delcarmen's wild pitch in the sixth inning moved Denard Span to third and Joe Mauer to second. At that point, the Red Sox decided to intentionally walk Jason Kubel. Justin Masterson was called in to relieve Delcarmen and hit the first batter he faced, Michael Cuddyer, forcing in a run.
Thor Nystrom is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.