"Today was pretty simple. I was trying to play with my location, feeling the grip, feeling my pitches first, throwing the first pitch for a strike, feeling comfortable with my mechanics," Doubront said. "I was really focusing and emphasizing my mechanics. I just go out there and tried to do what I was thinking in that moment and tried to get my work done."
Mike Napoli ripped a two-run homer to center in the fourth to put Boston in front. Jackie Bradley Jr., who is in competition with Grady Sizemore to be the starting center fielder, had two hits, an RBI and scored a run.
Brian Matusz, trying to win a spot in Baltimore's rotation, allowed two hits over two scoreless innings.
"[My stuff] felt pretty good, based off some of the swings on the changeup," said Matusz, who threw 35 pitches, 18 for strikes. "Some swings and misses and a couple outs. Had a few fastballs guys were taking and a few popups. So, giving up two hits that just found a hole, that's the game of baseball."
Edward Mujica, projected to be one of Boston's primary setup men this season, made his debut with his new team and fired a perfect third inning.
Delmon Young, battling for a roster spot with the Orioles, had hits in his first two at-bats while serving as the DH.
Up next: Red Sox closer Koji Uehara and setup man Junichi Tazawa will both see action for the first time this spring in Monday's 1:05 p.m. ET game at Bradenton, Fla., against the Pirates. Bradley, A.J. Pierzynski, Daniel Nava and Mike Carp all will be making the trip.
Ian Browne is a reporter for MLB.com. Read his blog, Brownie Points, and follow him on Twitter @IanMBrowne. This story was not subject to the approval of Major League Baseball or its clubs.