"We held him out as a precaution and hopefully he is back [Wednesday]," said Red Sox manager John Farrell.
Jackie Bradley Jr. replaced Victorino in right field.
Victorino played in 122 games for Boston last season and had surgery on his thumb in the offseason.
"Everything points to him being ready, even with the current stiffness," Farrell said. "We don't think this is going to keep him out of Opening Day."
Ian Browne is a reporter for MLB.com.Quinn Roberts is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.