But Gardenhire requested a challenge, and after a review the call was overturned, as first baseman Mike Napoli didn't get the tag down on Mauer in time.
As a result, Plouffe got another chance against right-hander Clay Buchholz but struck out looking two pitches later to strand Mauer and Dozier.
Rhett Bollinger is a reporter for MLB.com. Read his blog, Bollinger Beat, and follow him on Twitter @RhettBollinger. This story was not subject to the approval of Major League Baseball or its clubs.